Edward J. Handler, III, Esq.
Executive Chairman

Mr. Handler, a former senior partner and of counsel, Kenyon & Kenyon, LLP, has worked on pharmaceutical intellectual property cases over the years.  He has been responsible for assembling the TBP Pharma management team and for assembling the necessary consulting, licensing and IP agreements relating to C3.

Mr. Handler was granted a J.D. from the University of Virginia Law School and a B.S. from USMA (West Point). He is admitted to the bar in New York, the United States Supreme Court and the U.S. Court of Appeals for the Federal Circuit. Euromoney named him among the World’s Leading Patent Lawyers in 2003 and World’s Leading Trademark Lawyers in 2004. He is a U.S. Patent and Trademark Office Bar Member.


Mary Jane D. O’Connell, Ph.D., Esq
Chief Executive Officer and Board Member

Dr. O’Connell holds a B.S. in biological sciences from Fordham University, M.S. in natural sciences/chemistry and Ph.D. in chemistry/immunology from Roswell Park Cancer Institute, Buffalo, NY. Dr. O’Connell received her NIH NRSA postdoctoral training in immunology and molecular biology at NY Medical College and in immunochemistry at Memorial Sloan-Kettering Cancer Center where she was associated professionally for ten years as a cancer research scientist and senior research administrator. Following her J.D. from Fordham University School of Law, she was associated with Kenyon & Kenyon, LLP in pharmaceutical patent practice. Dr. O’Connell expects her MBA and M.S. in Healthcare Leadership degrees from Cornell University Johnson Graduate School of Management and Weill Cornell Medical College in 2019, bringing her expertise to focus on commercializing C3.

Dr. O’Connell has taught medical microbiology, immunology and molecular immunology at NYMC and federal regulatory agency policy and intellectual property law as Associate Dean for Academic Affairs at Fordham University. Dr. O’Connell is admitted to practice before the U.S. Patent and Trademark Office, U.S. Supreme Court, U.S. CAFC, U.S. District Courts in NY and NJ and NJ state bar.


Joseph E. Root, Esq.
General Counsel, Secretary and Board Member

Mr. Root is an attorney with 30 years of experience developing, protecting, and exploiting patent portfolios. He is the author of “Rules of Patent Drafting: Guidelines from Federal circuit Case Law”, published by Oxford University Press in 2011.

Mr. Root received a J.D., magna cum laude, from Wake Forest University, and a B.S. from the United States Military Academy, West Point, NY. He previously served as General Counsel to technology companies, public and private. He engaged in private practice with the New York office of Kenyon & Kenyon. Before attending law school, Mr. Root held engineering and production management positions with Corning and General Electric.


Seth Green
Board Member

Mr. Green has over 17 years of experience in business development, finance and strategy. While CEO of BREONICS, a Medical Device company in the Regenerative Medicine space, he led the company as it prepared for clinical trials. Previously, he served as a strategy consultant for Deloitte’s Strategy and Operations Practice where he advised C-Level executives on supply chain, logistics, manufacturing and turnarounds.

Prior to his business career, he served as an Aviation Officer in the U.S. Army. He led combat units in both Kosovo and Iraq, receiving the bronze star for his role in combat operations during the fall of Baghdad in March 2003. He is a 1996 graduate of the United States Military Academy at West Point and a 2005 graduate of the Tuck School of Business at Dartmouth where he received his MBA.


John F. Bronzo, Esq.
Vice President Business Development & Strategy and Board Member

Mr. Bronzo is is a pharmaceutical professional with more than 38 years of experience in corporate and tax law, and business development and strategy, at Pfizer, Inc. and the Law Firm of Cadwalader, Wickersham & Taft. He holds a B.A. and J.D. from Boston College, cum Laude, and an LLM in Tax Law from New York University.

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