The TBP team has deep research and development experience in pharmaceutical products, new company startup and development, and patent law. Parts of the team have worked together for nearly forty years, and each member of the team has deep experience in his/her area of expertise.

Edward J. Handler, III, Esq.
Executive Chairman

Mr. Handler, a former senior partner and of counsel, Kenyon & Kenyon, LLP, has worked on pharmaceutical intellectual property cases over the years.  He has been responsible for assembling the TBP Pharma management team and for assembling the necessary consulting, licensing and IP agreements relating to C3.

Mr. Handler was granted a J.D. from the University of Virginia Law School and a B.S. from USMA (West Point). He is admitted to the bar in New York, the United States Supreme Court and the U.S. Court of Appeals for the Federal Circuit. Euromoney named him among the World’s Leading Patent Lawyers in 2003 and World’s Leading Trademark Lawyers in 2004. He is a U.S. Patent and Trademark Office Bar Member.


Laura L. Dugan, M.D.
Principal Researcher

Dr. Dugan, the inaugural holder of the Larry L. Hillblom Chair in Geriatric Medicine at the University of California San Diego (UCSD), recently joined the faculty at Vanderbilt University Medical Center. She now directs Vanderbilt’s Division of Geriatric Medicine, a division of the Department of Medicine. She is board certified in both internal medicine and geriatrics. Dr. Dugan’s research focuses on the basic biology of nervous system aging and the role of free radical neurobiology in aging and neurodegenerative diseases. Her recent work has focused on rationally designed buckminsterfullerene derivatives as antioxidants and neuroprotective agents.

Dr. Dugan holds joint appointments in UC San Diego’s Departments of Medicine and Neurosciences. She received her SB in Life Sciences from the Massachusetts Institute of Technology, and her M.D. from the Ohio State University College of Medicine. She completed residency training in Internal Medicine at the UC San Francisco Children’s Hospital of San Francisco, and served as Chief Resident in Medicine her final year. She was a Presidential Scholar as an undergraduate and has been the recipient of a Dana Research Fellowship, a Paul Beeson Physician Scholars Award through the American Federation for Aging Research, a Hartford Foundation Award for Geriatric Research, a Hartford Leadership Scholars in Geriatric Medicine Award, the Kopolow Award for Geriatric Psychiatry and Neurology, and an Innovation Award from the St. Louis Academy of Sciences.


Richard G. Pellegrino, M.D., Ph.D.
Chief Scientific Officer

Dr. Pellegrino is a practicing neurologist and clinical researcher and is located in Hot Springs, Arkansas. Dr. Pellegrino has been Principal Investigator of more than 180 FDA Phase II and III clinical trials tests on past neurological and medical treatments.

Dr. Pellegrino is a former National Multiple Sclerosis Society fellow, Trustee of the American Academy of Pharmaceutical Physicians, and winner of the Ten Outstanding Young Americans award for 1995. He was awarded a Medical Scientist Training Program scholarship and received his M.D. and Ph.D. in neuroscience from the Albert Einstein College of Medicine of Yeshiva University, Bronx, NY. His post doctoral clinical and research training was conducted at Yale University Department of Pharmacology in New Haven CT., Columbia University Department of Neurology in New York City, NY, Penn State University Hospital Department of Neurology, in Hershey, PA, and the Westchester Medical Center Department of Internal Medicine in Westchester, NY.


John F. Bronzo, Esq.
Vice President, Business Development & Strategy

Mr. Bronzo is a pharmaceutical professional with more than 38 years of experience in corporate and tax law, business development and strategy. He previously served as General Counsel to Pfizer Animal Health, now Zoetis. Prior to joining Pfizer, he spent 8 years with the Law Firm of Cadwalader, Wickersham & Taft in New York.

Mr. Bronzo received a J. D. and a B. A., cum Laude, from Boston College, and an L.L.M. in Tax Law from New York University.


Joseph E. Root, Esq.
General Counsel, Secretary and Board Member

Mr. Root is an attorney with 30 years of experience developing, protecting, and exploiting patent portfolios. He is the author of “Rules of Patent Drafting: Guidelines from Federal circuit Case Law”, published by Oxford University Press in 2011. He previously served as General Counsel to sizeable companies, both public and private.

Mr. Root received a J.D., magna cum laude, from Wake Forest University, and a B.S. from the United States Military Academy, West Point, NY. He engaged in private practice with the New York office of Kenyon & Kenyon. Before attending law school, Mr. Root held engineering and production management positions with Corning and General Electric.


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